Micky van de Ven Brace Ends Everton's Unbeaten Streak at Brand New Stadium
The Dutch defender emerged as the first defender to net two goals in a Premier League game for Spurs since Jan Vertonghen in March 2013.
Match summary
The Spurs defender nods home twice in first half
The home side's Jake O'Brien has goal ruled after VAR review
Pape Matar Sarr scores final goal in dying moments
This loss is Everton's initial at their new ground
Micky van de Ven found the net twice as Tottenham prolonged their unbeaten run on the road in the top division and handed Everton their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their recently opened stadium at the dockside location, having departed their historic home behind after 133 years at the end of the previous campaign.
But Spurs captain Van de Ven pounced twice from corners in the opening 45 minutes to place their impressive record at risk, and they were unable to mount a comeback before the midfielder - assisted by former Toffees attacker Richarlison - headed home a third to seal the victory.
The Everton defender believed he had levelled the scores a short while after the defender's opener, glancing a powerful header past the Spurs keeper from an set-piece.
The Portuguese striker, in the meantime, failed to convert a handful of opportunities, while Vicario made a succession of fine saves to ensure Tottenham went five away games unbeaten in the English top flight.
But the VAR stepped in, instructing the match official to review the goal on the pitchside monitor and the referee decided that the winger and the attacker were in an illegal position and had interfered with the Spurs keeper.
This victory moves Thomas Frank's side up to third in the Premier League, a handful of points off local foes and table-toppers Arsenal.
Everton remain 14th and are six points clear of the relegation zone.
Spurs breakdown: Van de Ven fulfils duties at each end of pitch
Following a uninspiring midweek display in the Champions League against Monaco, where they mustered a mere attempts on goal, Frank chose Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The summer signing was unable to make much of an impact before being replaced for the substitute after 60 minutes on the pitch, but it turns out he proved unnecessary in the end.
Centre-back Van de Ven transformed into an attacking force to be feared.
Spurs' opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball back across the six-yard box for an unmarked the defender to head home.
And Ven de Ven - filling in as captain in Cristian Romero's unavailability - notched his next goal in added time as he outjumped the England keeper to head home.
Van de Ven was equally outstanding in defence, combining well with his defensive colleague as the pair dealt superbly with the 34 crosses sent their way by Everton.
Everton analysis: Everton missing striker's instinct
Everton's recent stadium had been a happy hunting ground, but it seems the novelty may have worn off somewhat and fans flocked to the exits after the midfielder's third for Tottenham.
The end in Everton's unbeaten home run will not be a massive worry for the manager, but their attacking woes are.
Beto and Thierno Barry - the Toffees' two recognised strikers - had scored just a single goal combined before the weekend's outing.
And they were unable to contribute to that miserable tally on a wet and gloomy night on Merseyside.
Beto's performance was summed up when he chose to bicycle-kick a clear chance from near the goal, even with having space and opportunity to readjust for a more conventional attempt that would have tested Vicario.
The substitute, too, was unable to make an impact after coming on for Beto in the 65th minute.
It wasn't for a lack of chance. Most of Everton's attacks came through Grealish and Ndiaye, who tirelessly delivered threatening crosses into the Spurs penalty area.
What next for these two sides?
Everton: The team head to the Stadium of Light in the top flight on Monday, 3 November at 8 PM.
Spurs: The London club travel to St James' Park on late October for their next round League Cup tie against Newcastle.